anti-H3K27me3 polyclonal antibody

Product name : anti-H3K27me3 polyclonal antibody

Catalog number : 6870-25

Supplier : Biovision

Price : 316 EUR

Size : H3K27me3 polyclonal antibody

More about:

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Entrez Gene : lysine demethylase 6B  (KDM6B)

Gene :

Gene ontology - Biological process : endothelial cell differentiation oxidation-reduction process positive regulation of transcription from RNA polymerase II promoter cellular response to hydrogen peroxide cell fate commitment response to activity response to fungicide inflammatory response to antigenic stimulus mesodermal cell differentiation histone H3-K27 demethylation

Gene ontology - Cellular component : nucleus nucleoplasm

Gene ontology - Molecular function : protein binding histone demethylase activity chromatin binding beta-catenin binding sequence-specific DNA binding metal ion binding dioxygenase activity histone demethylase activity (H3-K27 specific)

InterPro : JmjC domain  (RIOX1) Tetratricopeptide-like helical domain Lysine-specific demethylase 6B  (KDM6B)

Long gene name :

Name : Blotting, Western

PubMed : These results indicate that epigenetic derepression by JMJD3 controls mammalian epidermal differentiation. KDM6B may have a role in antigen-driven B-cell differentiation. KDM6A- and KDM6B-responsive Homeobox genes are expressed at significantly higher levels, suggesting that HPV16 E7 results in reprogramming of host epithelial cells H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERalpha ligand dependency Knockdown of JMJD3 in THP-1 cells affected expression of key genes in NF-kappaB, chemokine and CD40 signalling. JMJD3 at the nexus of epigenetic regulation of inflammation and the aging process demonstrated that miR-941 and KDM6B regulated the epithelial-mesenchymal transition process and affected cell migratory/invasive properties Demethylation of IGFBP5 by Histone Demethylase KDM6B Promotes Mesenchymal Stem Cell-Mediated Periodontal Tissue Regeneration by Enhancing Osteogenic Differentiation and Anti-Inflammation Potentials. We demonstrate that KDM6B plays a key role in clear cell renal cell carcinoma JMJD3 gene expression in renal cell carcinoma and bladder cancer.

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Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200

WikiPathWays : Pathways Affected in Adenoid Cystic Carcinoma Oxidative Stress Induced Senescence