anti-H6PD Antibody

Product name : anti-H6PD Antibody

Catalog number : 26-587

Supplier : proscience

Price : 180 EUR

Size : 50 ug

More about:

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Discovery year : 1999-11-26

Entrez Gene : hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase  (H6PD)  (TRV-CAC1-6)

Entrez gene record : 9563

GenBank acession : AJ012590

Gene : GDH

Gene ontology - Biological process : oxidation-reduction process glucose metabolic process pentose-phosphate shunt

Gene ontology - Cellular component : endoplasmic reticulum lumen

Gene ontology - Molecular function : NADP binding 6-phosphogluconolactonase activity glucose-6-phosphate dehydrogenase activity glucose 1-dehydrogenase [NAD(P)] activity

Havana BLAST/BLAT : OTTHUMG00000001768

Identity : 4225

InterPro : NAD(P)-binding domain  (HMGA1P8) 6-phosphogluconolactonase, DevB-type Glucosamine/galactosamine-6-phosphate isomerase  (TRV-CAC1-6) Glucose-6-phosphate dehydrogenase  (H6PD)  (TRV-CAC1-6) Glucose-6-phosphate dehydrogenase, C-terminal  (TRV-CAC1-6) Glucose-6-phosphate dehydrogenase, active site  (TRV-CAC1-6) Glucose-6-phosphate dehydrogenase, NAD-binding  (TRV-CAC1-6)

Kegg : Pentose phosphate pathway - Homo sapiens (human)

Locus : 1p36.22

Long gene name : hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase

Name : Blotting, Western

PubMed : Observational study of gene-disease association. (HuGE Navigator) Hexose-6-phosphate dehydrogenase directly determines the reaction direction of 11beta-Hydroxysteroid dehydrogenase1 in intact cells as an oxoreductase. Observational study of gene-disease association. (HuGE Navigator) Data show that failure to down-regulate HSD11B1 activity in patients with type 2 diabetes may contribute to the pathogenesis of T2DM. The aim of the work was to investigate the expression of HSD11B1, HSD11B2, H6PDH, and glucocorticoids receptor (GR) mRNA in subcutaneous adipose tissue (SAT) from obese women with or without polycystic ovary syndrome. Two new missense mutations in glucose-6-phosphate dehydrogenase gene associated with chronic hemolytic anemia. The observed constant expression of H6PD suggests that HSD11B1 acts as a reductase throughout the adipogenesis process in human ADMSCs and murine 3T3-L1 cells. Observational study of gene-disease association. (HuGE Navigator) findings indicate that the decrease in G6PDH activity that occurs after exposure of lung epithelial cells to chrysotile results from the carbonylation of G6PDH by TBARS Observational study of gene-disease association. (HuGE Navigator)

Pubmed identfication : 10349511

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

RefSeq identity : NM_004285

Synonyms : H6PD

Synonyms gene : GDH

Synonyms gene name : glucose dehyrogenase hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

Synonyms name : GDH/6PGL endoplasmic bifunctional protein

Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200