Anti- HACL1 Antibody

Product name : Anti- HACL1 Antibody

Catalog number : GEN2529036

Supplier : MBS Polyclonals

Price : 265 EUR

Size : 0.06 ml

More about:

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Discovery year : 2006-01-09

Entrez Gene : 2-hydroxyacyl-CoA lyase 1  (HACL1)

Entrez gene record : 26061

GenBank acession : AJ131753

Gene : HACL1

Gene ontology - Biological process : protein oligomerization fatty acid alpha-oxidation

Gene ontology - Cellular component : peroxisomal matrix intracellular membrane-bounded organelle peroxisome

Gene ontology - Molecular function : protein binding receptor binding magnesium ion binding identical protein binding carbon-carbon lyase activity cofactor binding thiamine pyrophosphate binding

Havana BLAST/BLAT : OTTHUMG00000129862

Identity : 17856

InterPro : DHS-like NAD/FAD-binding domain  (FANCD2)  (PSEN1) Thiamin diphosphate-binding fold Thiamine pyrophosphate enzyme, C-terminal TPP-binding Thiamine pyrophosphate enzyme, central domain Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain

Kegg : Peroxisome - Homo sapiens (human)

Locus : 3p25.1

Long gene name : 2-hydroxyacyl-CoA lyase 1

Name : Blotting, Western

PubMed : peroxisomal thiamine-pyrophosphate depending enzyme required for the degradation of phytanic acid, catalyzing the cleavage of 2-hydroxyphytanoyl-CoA lyase into formyl-CoA and pristanal 2-hydroxyphytanoyl-CoA lyase has a role in the breakdown of long chain 2-hydroxyfatty acids Transport of thiamine pyrophosphate into peroxisomes is dependent on HACL1 import, without requirement of a specific solute transporter. Data show that a easy assay for 2-hydroxyacyl-CoA lyase (HACL1) and sphingosine-1-phosphate lyase (SGPL1) activities was developed.

Pubmed identfication : 10468558 15644336

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

RefSeq identity : NM_012260

Synonyms : 2-HPCL PHYH2

Synonyms gene : HPCL

Synonyms gene name : 2-hydroxyphytanoyl-CoA lyase

Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200