anti-HADH/HCDH Antibody

Product name : anti-HADH/HCDH Antibody

Catalog number : 3264-100

Supplier : Biovision

Price : 316 EUR

Size : HADH/HCDH Antibody

More about:

Classification : WD repeat domain containing

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Discovery year : 2004-03-31

Entrez Gene : hydroxyacyl-Coenzyme A dehydrogenase  (HADH)

Entrez gene record : 51343

GenBank acession : AF083810

Gene : FZR1

Gene ontology - Biological process : oxidation-reduction process response to drug lipid metabolic process fatty acid beta-oxidation response to activity fatty acid metabolic process negative regulation of insulin secretion

Gene ontology - Cellular component : cytoplasm nucleoplasm mitochondrion mitochondrial inner membrane

Gene ontology - Molecular function : oxidoreductase activity NAD binding 3-hydroxyacyl-CoA dehydrogenase activity

Havana BLAST/BLAT : OTTHUMG00000180747

Identity : 24824

InterPro : NAD(P)-binding domain  (HMGA1P8) 3-hydroxyacyl-CoA dehydrogenase  (EHHADH) 3-hydroxyacyl-CoA dehydrogenase, conserved site 3-hydroxyacyl-CoA dehydrogenase, C-terminal 6-phosphogluconate dehydrogenase C-terminal domain-like 3-hydroxyacyl-CoA dehydrogenase, NAD binding 6-phosphogluconate dehydrogenase, domain 2

Kegg : Fatty acid degradation - Mus musculus (mouse) Valine, leucine and isoleucine degradation - Mus musculus (mouse) Lysine degradation - Mus musculus (mouse) Tryptophan metabolism - Mus musculus (mouse) Butanoate metabolism - Mus musculus (mouse) Fatty acid elongation - Mus musculus (mouse)

Locus : 19p13.3

Long gene name : fizzy and cell division cycle 20 related 1

Name : Blotting, Western

PubMed : Results demonstrate that L-3-hydroxyacyl-CoA dehydrogenase type II (HADH II/ABAD) modulates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity and suggests that mimetics may provide protective benefit in the treatment of Parkinson disease. SCHAD regulates insulin secretion through a KATP channel-independent mechanism. SCHAD deficiency causes hyperinsulinism by activation of GDH via loss of inhibitory regulation of GDH by SCHAD. SCHAD is involved in thermogenesis, in the maintenance of body weight, and in the regulation of nutrient-stimulated insulin secretion A physical association between short-chain 3-hydroxyacyl-coenzyme A dehydrogenase and important components of other key metabolic pathways. Most of the interactions were with enzymes in mitochondrial pathways.

Pubmed identfication : 9734353 11003657

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

RefSeq identity : NM_016263

Synonyms : HCDH1 CDH1 HCDH FZR FZR2 KIAA1242 CDC20C

Synonyms gene : HADHSC

Synonyms gene name : fizzy/cell division cycle 20 related 1 (Drosophila) fizzy/cell division cycle 20 related 1

Synonyms name : CDC20 homolog 1

Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200

WikiPathWays : Tryptophan metabolism Fatty Acid Beta Oxidation Fatty acid oxidation Fatty Acid Biosynthesis Mitochondrial LC-Fatty Acid Beta-Oxidation