Anti- HMG20B Antibody

Product name : Anti- HMG20B Antibody

Catalog number : GEN2524191

Supplier : MBS Polyclonals

Price : 348 EUR

Size : 0.12 ml

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Classification : Non-canonical high mobility group

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Discovery year : 1999-06-11

Entrez Gene : high mobility group 20B  (HMG20B)  (MIR20B)

Entrez gene record : 10362

GenBank acession : BC003505

Gene : HMG20B

Gene ontology - Biological process : transcription, DNA-templated regulation of transcription, DNA-templated cell cycle histone deacetylation blood coagulation positive regulation of neuron differentiation skeletal muscle cell differentiation negative regulation of protein sumoylation

Gene ontology - Cellular component : nucleoplasm chromosome nuclear body

Gene ontology - Molecular function : protein binding DNA binding protein heterodimerization activity histone deacetylase activity

Havana BLAST/BLAT : OTTHUMG00000150437

Identity : 5002

InterPro : High mobility group box domain  (HMG20A)

Locus : 19p13.3

Long gene name : high mobility group 20B

Name : Blotting, Western

PubMed : a novel function for HMG20b in cytokinesis is regulated by its interaction with the BRC repeats of BRCA2 Fresh insight into the mechanism by which the HMG20b-BRCA2 complex controls mitotic cell division, and implicate heterozygous HMG20b mutations affecting cytokinesis regulation in the genesis of human cancers molecular cloning, nucleotide and amino acid sequencing complex containing histone deacetylase complex containing histone deacetylase mediates repression of neuronal-specific genes. molecular Cloning of BRAF25, an alternatively spliced protein of BRAF35 Results demonstrating association of BRAF35 with KIF4 through the interaction of their respective alpha-helical coiled-coil domains is unique so far in mammals. we have examined Sox gene expression in 60 human primary gliomas. Transcripts from each of the six group E and group D genes were expressed in gliomas of various types and malignancy grades beta-dystrobrevin interacts with the HMG20 proteins iBRAF and BRAF35 HMG20B/BRAF35 forms heterodimers with HMG20A/iBRAF. Heterodimerization impairs HMG20B/BRAF35 sumoylation and interaction with the LSD1-CoREST complex.

Pubmed identfication : 10773667

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

RefSeq identity : NM_006339

Synonyms : SOXL HMGX2 BRAF35 SMARCE1r BRAF25 HMGXB2

Synonyms gene name : high-mobility group 20B

Synonyms name : HMG box domain containing 2

Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200