Capsid Protein Antibody, ALEXA FLUOR 647

Product name : Capsid Protein Antibody, ALEXA FLUOR 647

Catalog number : bs-10057R-A647

Supplier : Bioss Primary Conjugated Antibodies. ALEXA FLUOR

Price : 332.75 EUR

Size : 100ul

More about:

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Entrez Gene : transportin 3  (TNPO1P3)

Gene :

Gene ontology - Biological process : splicing factor protein import into nucleus

Gene ontology - Cellular component : cytoplasm intracellular membrane-bounded organelle nuclear membrane

Gene ontology - Molecular function : protein binding receptor activity identical protein binding nuclear localization sequence binding protein transporter activity

InterPro : Armadillo-type fold Armadillo-like helical Exportin-1/Importin-beta-like

Long gene name :

Name : Blotting, Western

PubMed : Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) Observational study of gene-disease association. (HuGE Navigator) Transportin 3 and importin alpha act as receptors and are required for effective nuclear import of HIV-1 integrase in virus-infected cells. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) IRF5-TNPO3 genetic variation is associated systemic lupus erythematosus. Results imply that the mechanism by which SR proteins are imported to the nucleus is conserved between Drosophila and humans and involves the nuclear import receptor transportin-SR Here the authors discover a link between the viral entry of HIV and its interaction with TRN-SR2. TNPO3 interacts with HIV-1 gag in the cytoplasm to assist HIV-1 infection after nuclear import. The TNPO3 gene is mapped within the Limb-girdle muscular dystrophy 1F critical interval and its 923-amino acid human gene product is also expressed in skeletal muscle. Data suggest that the HIV-1 integrase (IN)/transportin-SR2 (TRN-SR2) interaction interface is a potential target for antiviral therapy.

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Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200