ARHGEF2 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

Product name : ARHGEF2 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

Catalog number : LV079496

Supplier : ABM lentivectors

Price : 322.5 EUR

Size : 1.0 µg DNA

More about:

Classification : Phospholipases

Concept : Scope note: Process of growing viruses in live animals, plants, or cultured cells.

Discovery year : 2002-04-29

Entrez Gene : ubiquitin C  (UBC)

Entrez gene record : 50487

GenBank acession : AF220490

Gene : PLA2G3

Gene ontology - Biological process : positive regulation of transcription from RNA polymerase II promoter MAPK cascade T cell receptor signaling pathway Wnt signaling pathway positive regulation of apoptotic process negative regulation of canonical Wnt signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process DNA damage response, detection of DNA damage error-free translesion synthesis endoplasmic reticulum mannose trimming

Gene ontology - Cellular component : extracellular space plasma membrane nucleoplasm endoplasmic reticulum membrane endosome membrane myelin sheath vesicle endoplasmic reticulum quality control compartment mitochondrial outer membrane endocytic vesicle membrane

Gene ontology - Molecular function : protein binding RNA binding protease binding

Havana BLAST/BLAT : OTTHUMG00000151255

Identity : 17934

InterPro : Ubiquitin-related domain Ubiquitin domain  (UBLCP1) Ubiquitin conserved site Ubiquitin  (USP51)

Kegg : PPAR signaling pathway - Homo sapiens (human)

Locus : 22q12.2

Long gene name : phospholipase A2 group III

Name : Virus Cultivation

PubMed : Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase. Data indicate that modification of NEMO with linear di-ubiquitin is sufficient for full NF-kappaB activation. Chicago Sky Blue 6B (CSB6B) binds directly to the beta-groove of ubiquitin and could inhibit the binding of ubiquitin to chemokine (C-X-C motif) receptor 4 (CXCR4), a cell surface ubiquitin receptor. USP4 requires its N-terminal DUSP-Ubl domain to achieve full catalytic turnover by promoting ubiquitin exchange. Data indicate that heat shock protein 90kDa (Hsp90) inhibition suppresses 26S proteasome remodeling, unanchored ubiquitin chain production, and aggresome clearance. Data suggest that ubiquitin (Ub) binding provides a negative feedback loop upon NOD1 and NOD2 (nucleotide-binding oligomerization domain-containing proteins)-dependent activation of receptor-interacting protein kinase 2 (RIP2). CHBP is an inhibitor of the ubiquitination pathway; it deamidated Gln40 in ubiquitin and ubiquitin-like protein NEDD8 in vitro and during Burkholderia infection; Cif deamidated NEDD8, abolishing activity of neddylated Cullin-RING ubiquitin ligases The human ubiquitin C promoter transgene might be useful to selectively target projections of brain neurons. These results reveal an unanticipated mode of Ube2g2 self-association that allows Ube2g2 to effectively engage two ubiquitins to specifically synthesize Lys48-linked ubiquitin chains.

Pubmed identfication : 10713052

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

RefSeq identity : NM_015715

Synonyms : GIII-SPLA2

Synonyms gene name : phospholipase A2, group III

Tree numbers : E01.370.225.875.970 E05.200.875.970

WikiPathWays : Proteasome Degradation DNA Replication