ARHGEF4 Antibody - C-terminal region

Product name : ARHGEF4 Antibody - C-terminal region

Catalog number : OAAB14205

Supplier : aviva

Price : 424 EUR

Size : one vial

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Classification : Rho guanine nucleotide exchange factors Pleckstrin homology domain containing

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Discovery year : 2000-04-11

Entrez Gene : Rho guanine nucleotide exchange factor (GEF) 4  (ARHGEF2)  (ARHGEF4)

Entrez gene record : 50649

GenBank acession : AL137289

Gene : ARHGEF4

Gene ontology - Biological process : intracellular signal transduction regulation of Rho protein signal transduction lamellipodium assembly filopodium assembly

Gene ontology - Cellular component : cytoplasm

Gene ontology - Molecular function : protein domain specific binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity Rac guanyl-nucleotide exchange factor activity

Identity : 684

InterPro : Pleckstrin homology domain  (PLEKHA7) PH domain-like  (AGAP4) SH3 domain  (SBK1) Dbl homology (DH) domain Guanine-nucleotide dissociation stimulator, CDC24, conserved site

Kegg : Regulation of actin cytoskeleton - Mus musculus (mouse)

Locus : 2q21.1

Long gene name : Rho guanine nucleotide exchange factor 4

Name : Blotting, Western

PubMed : these results demonstrate potent anti-inflammatory effects by HGF and delineate a key role of Asef in the mediation of the HGF barrier protective and anti-inflammatory effects. Asef and Asef2 are required for adenoma formation in Apc(Min/ )mice. Asef has a role in HGF-mediated protection against endothelial hyperpermeability and lung injury.

Pubmed identfication : 10873612

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

Synonyms : STM6 KIAA1112 ASEF

Synonyms gene name : Rho guanine nucleotide exchange factor (GEF) 4

Synonyms name : APC-stimulated guanine nucleotide exchange factor

Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200

WikiPathWays : Regulation of Actin Cytoskeleton