ARID1B Antibody, ALEXA FLUOR 350

Product name : ARID1B Antibody, ALEXA FLUOR 350

Catalog number : bs-12520R-A350

Supplier : Bioss Primary Conjugated Antibodies. ALEXA FLUOR

Price : 332.75 EUR

Size : 100ul

More about:

Classification : AT-rich interaction domain containing

Concept : Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Discovery year : 2004-01-28

Entrez Gene : AT-rich interaction domain 1B  (ARID1B)  (NBN)

Entrez gene record : 57492

GenBank acession : AF521671

Gene : ARID1B

Gene ontology - Biological process : transcription, DNA-templated covalent chromatin modification neuron-neuron synaptic transmission dendritic spine development chromatin-mediated maintenance of transcription dendritic cell dendrite assembly

Gene ontology - Cellular component : cytosol plasma membrane nucleoplasm SWI/SNF complex nBAF complex

Gene ontology - Molecular function : protein binding DNA binding transcription coactivator activity

Havana BLAST/BLAT : OTTHUMG00000015890

Identity : 18040

InterPro : ARID DNA-binding domain  (HLA-DOA) Armadillo-type fold Armadillo-like helical SWI/SNF-like complex subunit BAF250/Osa  (ARID1A)  (SMARCA1) SWI/SNF-like complex subunit BAF250, C-terminal  (ARID1A)  (SMARCA1)

Locus : 6q25.3

Locus Specific Databases : LRG_861

Long gene name : AT-rich interaction domain 1B

Name : Blotting, Western

PubMed : Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 6A3-5 expression is associated with alpha-smooth muscle cell actin in mesangial cells, arteriolar smooth muscle cells, and interstitial myofibroblasts.could potentially be a novel early vascular marker of acute and chronic renal ischemic stress Analysis of DNA-binding behaviour indicates that ARID1B binds DNA in a non-sequence-specific manner similar to ARID1A The chromatin remodeling factor ARID1B had a very similar pattern of expression with an incremental increase in HPFH and decreased expression in deltabeta-thalassemia. Haploinsufficiency of ARID1B, a member of the SWI/SNF-A chromatin-remodeling complex, is a common cause of ID. loss of ARID1A and ARID1B alleles cooperatively promotes cancer formation but also results in a unique functional dependence The BAF complex, including both ARID1A and ARID1B, contributes to DNA repair and cellular resistance to ionizing radiation and cisplatin. Chromatin-Remodeling-Factor ARID1B Represses Wnt/beta-Catenin Signaling. Gonadal mosaicism in ARID1B gene causes intellectual disability and dysmorphic features in three siblings. This study demonstrate that ARID1B is required for neuronal differentiation in the developing brain, such as in dendritic arborization and synapse formation.

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

RefSeq identity : NM_020732

Synonyms : KIAA1235 ELD/OSA1 p250R BAF250b DAN15 6A3-5

Synonyms gene name : AT rich interactive domain 1B (SWI1-like)

Tree numbers : E05.196.401.143 E05.301.300.096 E05.478.566.320.200 E05.601.262 E05.601.470.320.200

WikiPathWays : Prostate Cancer