Autographa californica nuclear polyhedrosis virus P18 protein (P18)

Product name : Autographa californica nuclear polyhedrosis virus P18 protein (P18)

Catalog number : GEN1005367.Mammalian Cell

Supplier : MBS Recombinant

Price : 2028 EUR

Size : 100ug

More about:

Discovery year : 1999-07-22

Entrez Gene : cyclin dependent kinase inhibitor 2C  (CDKN2C)

Entrez gene record : 9521

Expression system : Mammalian Cell

GenBank acession : AF054186

Gene : EEF1E1

Gene ontology - Biological process : negative regulation of cell growth negative regulation of cell proliferation G1/S transition of mitotic cell cycle negative regulation of phosphorylation cell cycle arrest regulation of cyclin-dependent protein serine/threonine kinase activity oligodendrocyte differentiation negative regulation of cyclin-dependent protein serine/threonine kinase activity

Gene ontology - Cellular component : nucleus cytoplasm cytosol

Gene ontology - Molecular function : protein binding protein kinase binding cyclin-dependent protein serine/threonine kinase inhibitor activity

General description : P18 protein (P18) is a recombinant protein expressed in Mammalian Cell . The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.

Havana BLAST/BLAT : OTTHUMG00000014221

Identity : 3212

InterPro : Ankyrin repeat-containing domain  (ANKLE1) Ankyrin repeat  (ANKRD19P)

Kegg : Transcriptional misregulation in cancer - Homo sapiens (human) HTLV-I infection - Homo sapiens (human) Cell cycle - Homo sapiens (human)

Locus : 6p24.3

Long gene name : eukaryotic translation elongation factor 1 epsilon 1

PubMed : Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) Expression of p15, p18 and p27 was not generally related to the MEN1 gene mutational status of the investigated 18 pancreatic endocrine tumours. Observational study of gene-disease association. (HuGE Navigator) Observational study of gene-disease association. (HuGE Navigator) Observational study of gene-disease association. (HuGE Navigator) propose that the contrasting behavior of the two very similar INK4 proteins could reflect their respective roles in senescence versus differentiation p18INK4c may function as a tumor suppressor in Hodgkin lymphoma, and inactivation may contribute to cell cycle deregulation and defective terminal differentiation of the Reed-Sternberg cells. NaBu-mediated p18( INK4C ) regulation played a role in cell cycle arrest and erythroid differentiation in K562 cells. P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma up-regulated HULC promotes proliferation of hepatoma cells through suppressing p18

Pubmed identfication : 9653160

RefSeq identity : NM_004280

Synonyms : AIMP3

Synonyms gene : P18

Synonyms name : aminoacyl tRNA synthetase complex-interacting multifunctional protein 3

WikiPathWays : G1 to S cell cycle control Signaling Pathways in Glioblastoma Vitamin D Receptor Pathway