C2orf69 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

Product name : C2orf69 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

Catalog number : LV094064

Supplier : ABM lentivectors

Price : 322.5 EUR

Size : 1.0 µg DNA

More about:

Classification : Phospholipases

Concept : Scope note: Process of growing viruses in live animals, plants, or cultured cells.

Discovery year : 2002-04-29

Entrez Gene : ubiquitin C  (UBC)

Entrez gene record : 50487

GenBank acession : AF220490

Gene : PLA2G3

Gene ontology - Biological process : positive regulation of I-kappaB kinase/NF-kappaB signaling G2/M transition of mitotic cell cycle regulation of necroptotic process Fc-epsilon receptor signaling pathway macroautophagy Notch signaling pathway nucleotide-binding oligomerization domain containing signaling pathway ion transmembrane transport endosomal transport SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Gene ontology - Cellular component : cytosol plasma membrane nucleoplasm extracellular exosome endoplasmic reticulum membrane endosome membrane vesicle endoplasmic reticulum quality control compartment mitochondrial outer membrane host cell

Gene ontology - Molecular function : protein binding RNA binding protease binding

Havana BLAST/BLAT : OTTHUMG00000151255

Identity : 17934

InterPro : Ubiquitin-related domain Ubiquitin domain  (UBLCP1) Ubiquitin conserved site Ubiquitin  (USP51)

Kegg : PPAR signaling pathway - Homo sapiens (human)

Locus : 22q12.2

Long gene name : phospholipase A2 group III

Name : Virus Cultivation

PubMed : Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase. Studies indicate that Mdm2 has the ability to catalyze both mono- and poly-ubiquitination of p53. USP4 requires its N-terminal DUSP-Ubl domain to achieve full catalytic turnover by promoting ubiquitin exchange. The presence of ubiquitin mainly in the nuclei and in the cytoplasm of BPH and prostatic adenocarcinoma, respectively, may suggest a role of ubiquitin in the development of the above mentioned conditions The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin. Studies indicate that the involvement of the degradation-linked K48-ubiquitin signal and the proteasome at the sites of DSBs. UbcH5c~Ubiqitin binding stabilizes an active conformation of the Shigella flexneri OspG kinase, greatly enhancing its activity. Static HMG-20 structure is derived from high precision residual dipolar couplings measured in a drug-based liquid crystalline phase using NMR spectroscopy. Studies suggest that quantitative proteomic approaches would set a standard for elucidating biochemical mechanisms of Ubiquitin (UB)-driven signaling systems. Data show that discoidin domain receptor 2 (DDR2) is linked to a polyubiquitin (Ub) chain predominantly through lysine K27 conjugation and slightly through K33.

Pubmed identfication : 10713052

Qualifiers : classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics

RefSeq identity : NM_015715

Synonyms : GIII-SPLA2

Synonyms gene name : phospholipase A2, group III

Tree numbers : E01.370.225.875.970 E05.200.875.970

WikiPathWays : Proteasome Degradation DNA Replication