C2orf71 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

Product name : C2orf71 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

Catalog number : LV094076

Supplier : ABM lentivectors

Price : 1125 EUR

Size : 1.0 µg DNA

More about:

Classification : Phospholipases

Concept : Scope note: The in vitro fusion of GENES by RECOMBINANT DNA techniques to analyze protein behavior or GENE EXPRESSION REGULATION, or to merge protein functions for specific medical or industrial uses.

Discovery year : 2002-04-29

Entrez Gene : ubiquitin C  (UBC)

Entrez gene record : 50487

GenBank acession : AF220490

Gene : PLA2G3

Gene ontology - Biological process : regulation of hematopoietic stem cell differentiation protein ubiquitination fibroblast growth factor receptor signaling pathway MyD88-independent toll-like receptor signaling pathway glycogen biosynthetic process Notch signaling pathway DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest error-free translesion synthesis nucleotide-excision repair, DNA incision, 5'-to lesion nucleotide-excision repair, DNA duplex unwinding

Gene ontology - Cellular component : extracellular space nucleus cytosol plasma membrane extracellular exosome endoplasmic reticulum membrane endosome membrane vesicle mitochondrial outer membrane host cell

Gene ontology - Molecular function : protein binding RNA binding protease binding

Havana BLAST/BLAT : OTTHUMG00000151255

Identity : 17934

InterPro : Ubiquitin-related domain Ubiquitin domain  (UBLCP1) Ubiquitin conserved site Ubiquitin  (USP51)

Kegg : PPAR signaling pathway - Homo sapiens (human)

Locus : 22q12.2

Long gene name : phospholipase A2 group III

Name : Artificial Gene Fusion

PubMed : Chicago Sky Blue 6B (CSB6B) binds directly to the beta-groove of ubiquitin and could inhibit the binding of ubiquitin to chemokine (C-X-C motif) receptor 4 (CXCR4), a cell surface ubiquitin receptor. the mechanical stability of ubiquitin is linkage dependent Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain Studies indicate that indicating that the inhibition of the ubiquitin-proteasome system could be used as a novel approach for cancer therapy. Studies indicate that the involvement of the degradation-linked K48-ubiquitin signal and the proteasome at the sites of DSBs. Studies indicate that Ubiquitin- and SUMO-mediated modification pathways have emerged as key players in regulating damage-induced template switching. analysis of cold-induced changes in the protein ubiquitin Ubiquitin's regulatory mechanisms of expression in heart failure patients' cardiomyocytes. (review) This article reviews the recent advances in proteomics of HMG20 and reveals novel networks and associations with human disease.[review] The authors now report the crystal structure of a human Parkin-phosphoubiquitin complex, which shows that phosphoubiquitin binding induces movement in the 'in-between RING' (IBR) domain to reveal a cryptic ubiquitin-binding site.

Pubmed identfication : 10713052

Qualifiers : drug effects, methods, radiation effects

RefSeq identity : NM_015715

Synonyms : GIII-SPLA2

Synonyms gene name : phospholipase A2, group III

Tree numbers : E05.393.220.250

WikiPathWays : Proteasome Degradation DNA Replication